Hyperspectral imaging for early shock detection - a prospective observational trial

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00030986

Enrollment

250

Registered

2022-12-27

Start date

2023-01-02

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

T07 T79.4 R57.1

Interventions

Group 1: Patients with clinical signs of shock in the shock room with guideline-based diagnostics and therapy and image acquisition using a hyperspectral camera from one hand with extended coagulation

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Individuals with condition following trauma regardless of age - Admission via surgical shock room - Consent to the study

Exclusion criteria

Exclusion criteria: - Prisoners - Refusal by patient or legal representative

Design outcomes

Primary

Measure	Time frame
Difference in tissue oxygenation (StO2) of hyperspectral imaging in subjects with and without shock after trauma.	—

Secondary

Measure	Time frame
- Hyperspectral measurement of various microcirculatory parameters (near-infrared perfusion index, tissue hemoglobin index, tissue water index) on one hand - Comparison of near-infrared perfusion index, tissue hemoglobin index, tissue water index in hemodynamically stable subjects with subjects with hemodynamic instability (shock). - Comparison of near-infrared perfusion index, tissue hemoglobin index, tissue water index in different types of shock (hemorrhagic, obstructive, distributive) - Correlation of microcirculatory parameters with 30-day morbidity and mortality (ISS score, SOFA score, TRISS score) - Correlation of various biomarkers (e.g., lactate, C-reactive protein, interleukin-6, hemoglobin, procalcitonin, myoglobin, troponin T/I, D-dimers) with hyperspectrally recorded microcirculatory parameters - Correlation of coagulation diagnostics (e.g. factor XIII, thrombelostography) with hyperspectrally recorded microcirculatory parameters - Correlation of hyperspectrally recorded microcirculatory parameters and intensive care and hospital length of stay - Correlation of hyperspectrally recorded microcirculatory parameters with the onset of ROSC in traumatic circulatory arrest	—

Measure

Time frame

- Hyperspectral measurement of various microcirculatory parameters (near-infrared perfusion index, tissue hemoglobin index, tissue water index) on one hand - Comparison of near-infrared perfusion index, tissue hemoglobin index, tissue water index in hemodynamically stable subjects with subjects with hemodynamic instability (shock). - Comparison of near-infrared perfusion index, tissue hemoglobin index, tissue water index in different types of shock (hemorrhagic, obstructive, distributive) - Correlation of microcirculatory parameters with 30-day morbidity and mortality (ISS score, SOFA score, TRISS score) - Correlation of various biomarkers (e.g., lactate, C-reactive protein, interleukin-6, hemoglobin, procalcitonin, myoglobin, troponin T/I, D-dimers) with hyperspectrally recorded microcirculatory parameters - Correlation of coagulation diagnostics (e.g. factor XIII, thrombelostography) with hyperspectrally recorded microcirculatory parameters - Correlation of hyperspectrally recorded microcirculatory parameters and intensive care and hospital length of stay - Correlation of hyperspectrally recorded microcirculatory parameters with the onset of ROSC in traumatic circulatory arrest

—

Countries

Germany

Contacts

Public ContactStephan Katzenschlager

Universitätsklinikum Heidelberg, Klinik für Anästhesiologie

Stephan.Katzenschlager@med.uni-heidelberg.de+49 62215639683

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Aug 8, 2026