Women's brain health in healthy volunteers
Conditions
Interventions
Group 1: One group, healthy controls, observed 6 timepoints across the menstrual cycle (no intervention)
Sponsors
Max Planck Institute for Human Cognitive and Brain Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: right-handed, a BMI 18.5–29 kg/m2, without any neurological or psychiatric illness, regular menstrual cycle
Exclusion criteria
Exclusion criteria: prescription medication or supplement use; tobacco use; positive drug or pregnancy tests; current use or use of hormonal contraceptives within the past 6 months; current or past hormone therapy; having been pregnant, postpartum, breastfeeding, or had an abortion within one year of the study; DSM-IV Axis I Disorders and Axis II Disorders; presence of premenstrual mood symptoms
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Association of ovarian hormones (estradiol and progesterone) with brain volume (hippocampal and medial temporal lobe subregions) | — |
Secondary
| Measure | Time frame |
|---|---|
| Control analyses (association of ovarian hormones with cerebral spinal fluid, cerebral blood flow, and precentral gyrus volume) | — |
Countries
Germany
Contacts
Public ContactJulia Sacher
Max Planck Institute for Human Cognitive and Brain Sciences
Outcome results
None listed