Analysis of cell-specific receptors in eczematized skin and correlation of cytokine expression with the molecular adaptation of staphylococci during infection

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00030934

Enrollment

Registered

2022-12-14

Start date

2024-03-13

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atopic dermatitis

Interventions

Group 1: The study of marker expression in inflammatory skin is performed by taking a biopsy of diseased skin (4mm punch biopsy) under local anesthesia.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: All adult patients with atopic dermatitis from the Aachen Dermatology Clinic who consult the dermatology outpatient clinic or provide a nasal and skin swab for microbiological diagnosis during their inpatient stay and have lesional skin sites and agree with the study protocol.

Exclusion criteria

Exclusion criteria: Patient refusal, patient unable to consent, and minors < 18 years of age.

Design outcomes

Primary

Measure	Time frame
The aim of the study is to compare the gene expression pattern and activated virulence factors of staphylococci during skin infection with quantitative cytokine expression and receptor expression on lesional and non-lesional skin.	—

Countries

Germany

Contacts

Public ContactAmir Yazdi

Hautklinik, RWTH Aachen

ayazdi@ukaachen.de+49241750188330

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Jun 11, 2026