Observational study for measuring lithium concentrations in venous blood and saliva

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00030846

Enrollment

Registered

2022-12-12

Start date

2023-01-26

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

F32 F31

Interventions

Group 1: Inpatients with an indicated lithium therapy

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: -Diagnosis of a unipolar depression or a bipolar affective disorder (I and II) -Current or planned lithium therapy in inpatient treatment -Ability to consent -Signed written consent

Exclusion criteria

Exclusion criteria: -Diagnosis of an antisocial or other heavy personality disorder -Schizophrenia -Strong cognitive impairment, e.g. dementia or reduced intelligence -Withdrawal of consent -Renal insufficiency stage 3 and higher (GFR 30-59), severe cardiac or circulatory disease -Institutionalization by court or official order (according to AMG § 40 (1) 4)

Design outcomes

Primary

Measure	Time frame
Measuring the correlation between lithium concentrations in venous blood and saliva	—

Secondary

Measure	Time frame
Evaulation of the potential of saliva as a more accessible medium for measuring the lithium concentration	—

Countries

Germany

Contacts

Public ContactMarcella Rietschel

Zentralinstitut für Seelische Gesundheit

marcella.rietschel@zi-mannheim.de+4962117036051

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026