Retrospective analysis of perioperative patients with and without substitution for acquired FXIII deficiency

Retrospective analysis of perioperative patients with and without substitution for acquired FXIII deficiency - -Mild XIII Substitution Trial-

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00030705

Enrollment

500

Registered

2022-11-09

Start date

2022-12-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acquired FXIII deficiency

Interventions

Group 1: Patients with FXIII deficiency after surgery with and without FXIII substitution

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age=18 Surgery and FXIII activity = 80%

Exclusion criteria

Exclusion criteria: Hereditary FXIII deficiency

Design outcomes

Primary

Measure	Time frame
- Does FXIII activity correlate with the rate of perioperative complications requiring intervention? - What are the average FXIII activities in perioperative factor XIII deficiency?	—

Secondary

Measure	Time frame
- How much and how often was FXIII substituted on average? - At what level or with what indication is FXIII substituted? - Does factor XIII activity correlate with perioperative transfusion requirements? - Does the level of lowest/highest factor XIII activity influence the duration of ventilation, intensive care stay, and mortality?	—

Countries

Germany

Contacts

Public ContactFelix Schmitt

Universitätsklinikum HeidelbergKlinik für Anästhesiologie

Felix.Schmitt@med.uni-heidelberg.de062215639421

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026