Evaluation of the metabolic situation on pregnancy course and outcome in patients with phenylketonuria

Evaluation of the metabolic situation on pregnancy course and outcome in patients with phenylketonuria - Pregnancy_PKU

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00030654

Enrollment

Registered

2022-11-03

Start date

2022-11-02

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

E70.0 E70.1

Interventions

Group 1: Female patients with PKU who have at least one child are asked about pregnancy course and health of their child by a questionnaire.

Eligibility

Sex/Gender

Female

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: - Female patients with hyperphenylalaninemia (phe concentrations > 360 µmol/l), who have delivered at least one child - age at least 18 years

Exclusion criteria

Exclusion criteria: cognitive impairment (inability to understand ICF)

Design outcomes

Primary

Measure	Time frame
Does planning of a pregnancy and intensivation of preconceptional phe concentrations in patients with PKU influence - metabolic situation (phe and tyr concentrations) - occurence of maternal PKU syndrome	—

Countries

Germany

Contacts

Public ContactAlboren Shtylla

Klinik für Endokrinologie, Diabetologie, Stoffwechsel und Klinische Chemie; Universitätsklinikum Heidelberg

Innere_1@med.uni-heidelberg.de+49 6221 56 8787

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026