HEALTHY VOLUNTEERS
Conditions
Interventions
Group 1: Group 1: Examination of the pH value in saliva during the last four days of the examination period.
Group 2: Group 2: Examination of the pH value in the biofilm
during the last four days of t
Sponsors
Universitätsklinikum Schleswig-Holstein, Campus KielKlinik für Zahnerhaltungskunde und Parodontologie
Eligibility
Sex/Gender
All
Age
22 Years to 55 Years
Inclusion criteria
Inclusion criteria: Generally healthy persons to whom the exclusion criteria do not apply.
Exclusion criteria
Exclusion criteria: Exclusion criteria for participation in the study are a BMI 29.5 kg/m², metabolic or endocrine diseases, malabsorption syndrome, allergies, smoking, alcohol and drug abuse, medication (such as e.g. antidepressants, antibiotics), presence of a defibrillator or pacemaker, nickel allergy, known allergies to the materials used, MRI examination scheduled during the study period, reflux disease, bulimia, medical conditions (such as HIV, hepatitis, or diabetes), and epilepsy. Further dental exclusion criteria are existing tooth structure defects requiring treatment, a periodontal screening index (PSI) >2, professional dental cleaning less than 4 weeks ago, no stable occlusion, orthodontic treatment performed at the time of the study, wearing of an occlusal splint (''grinding splint''), and no sufficient number of teeth present, i.e., no terminal molar in the fourth or third quadrant and more than 2 missing teeth per quadrant. Also excluded are dental students or employees in a dependent relationship.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pH measurement in saliva and biofilm over four days | — |
Secondary
| Measure | Time frame |
|---|---|
| Saliva flow rate, saliva buffer capacity, plaque volume (API), biofilm sample | — |
Countries
Germany
Contacts
Public ContactChristof E. Dörfer
Universitätsklinikum Schleswig-Holstein, Campus KielKlinik für Zahnerhaltungskunde und Parodontologie
Outcome results
None listed