Covid-19 related olfactory dysfunction
Conditions
Interventions
Group 1: Patients with Covid-19-related olfactory loss.
Questionnaire survey at 5 time points(T1:olfactory ability test at baseline
T2: 1 month later, body odor perception odor experiment at follow-up for a subgroup (N = 50) of the total sample. T3: 3 months later
T4: 6 months later, T5: 12 months later).
Sponsors
Klinik und Poliklinik für Psychotherapie und Psychosomatik
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Gender: both, male and female; Minimum Age: 18 years; Covid-19-related olfactory loss
Exclusion criteria
Exclusion criteria: Significant other health impairments (e.g., diabetes mellitus, renal insufficiency) that may be associated with disorders of olfactory function; Acute or pronounced chronic inflammation of the nose and paranasal sinuses; Additional relevant pre-existing or concomitant diseases in the ENT area, or with underlying brain-organic diseases; Current pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Influence of covid-19-related olfactory loss on psychological well-being and general life satisfaction, as well as olfactory loss-related changes in sexuality and relationship quality within committed partnerships and influence on relationship quality of patients with their biological children. As primary outcome, we are interested in general life satisfaction as well as mental health (assessed with WHO Wellbeing Index; PHQ-4, Löwe et al., 2010; BDI-II, Hautzinger et al., 2010), relationship quality in partnership (Partnership Satisfaction Questionnaire; Kliem et al., 2012) and in parent-child relationship (PBQ, Brockington et al., 2006). These parameters are collected at all 5 measurement time points by means of questionnaires. | — |
Secondary
| Measure | Time frame |
|---|---|
| Perception of body odors within the partnership and parent-child relationship (Pleasantness, Intensity, Identification). In an additional experiment after T2 for N = 50 participants, body odors of the partner (N=25) and of the own child (N=25) will be evaluated in comparison to age- and sex-matched body odors of healthy control subjects. The following outcomes will be collected: Identification of body odor (partner/child vs. unknown body odor); pleasantness rating, intensity rating of odor. | — |
Countries
Germany
Contacts
Public ContactLaura Schäfer
Klinik und Poliklinik für Psychotherapie und Psychosomatik
Outcome results
None listed