Empirical study with a focus on the neural mechanisms that play a role in the enhancement of episodic memory formation induced by prediction errors in the context of fear conditioning, both retroactively and prospectively. Results can be meaningful regarding application-related contexts such as school or university and diseases associated with altered memory processes (e.g. post-traumatic stress disorder). To investigate these mechanisms, the intervention group receiving inhibitory stimulation
Conditions
Interventions
Group 1: Intervention group:
Participants will undergo neuronavigated TMS which will temporarily inhibit the right superior parietal cortex applied before and during performance of the fear conditioni
Sponsors
Universität Hamburg
Eligibility
Sex/Gender
All
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: - native German speakers - right-handedness
Exclusion criteria
Exclusion criteria: - psychology studies - Current physical or mental illness - history of neurological or mental illness (e.g. neurological surgery, epilepsy or single seizure, head trauma) - any metal/implants in the body - prescriptive medication - substance abuse -Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To investigate the neural mechanisms involved in the retroactive and prospective enhancement of episodic memory induced by prediction errors. For this purpose, participants will undergo either a TMS upon the right superior parietal cortex or a Sham stimulation before performing a fear conditioning task with a surprise recognition test. Physiological measures will be recorded during the fear conditioning task. This results in two experimental groups. | — |
Secondary
| Measure | Time frame |
|---|---|
| Improved understanding of the neural mechanisms of prediction error induced episodic memory enhancement | — |
Countries
Germany
Contacts
Public ContactKaja Loock
Universität Hamburg
Outcome results
None listed