E88.28
Conditions
Interventions
Group 1: lipedema patients: assessment of the pressure pain threshold and vibration detection threshold, molecularpathological investigation of tissue samples.
Group 2: obese controls: assessment of
Sponsors
Universitätsklinikum Köln
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Lipedema: Diagnosis of lipedema, BMI 35 kg/m2, waist > 100 cm; Normalweight non-lipedema: BMI < 30 kg/m2, waist < 80 cm
Exclusion criteria
Exclusion criteria: restrains in communication skills; diseases that affect the sensory nervous system, skin issitations at the testing areas; topical application of analgesics at the testing areas, alterations in pain perception or other diagnoses of chronic pain
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Characterization of the clinical phenotype by assessment of pressure pain threshold and vibration detection threshold by quantitativ sensory testing according to the protocol of the DFNS, as well as the Germain Pain Questionnaire | — |
Secondary
| Measure | Time frame |
|---|---|
| Characterization of histological alterations of nociceptive skin innervation, characterization of alterations in cytokines and growth factors | — |
Countries
Germany
Contacts
Public ContactRebecca Dinnendahl
Translationale SchmerzforschungKlinik für Anästhesiologie und Operative IntensivmedizinUniversitätsklinikum Köln (AöR)
Outcome results
None listed