Effects of prenatal diagnosis of a congenital heart defect on further pregnancy and emotional burden of the expectant mother

Effects of prenatal diagnosis of a congenital heart defect on further pregnancy and emotional burden of the expectant mother - Prenatal diagnosis Congenital heart defect – what now?

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00030479

Enrollment

260

Registered

2022-10-25

Start date

2023-01-02

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Q24 F43.8 F32

Interventions

Group 1: Pregnant women with prenatal diagnosis CHD - questionnaires regarding maternal emotional burden and collection of fetal and infant clinical parameters Group 2: Pregnant women without prenatal

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: adult pregnant women with a fetus with congenital heart defect. Adult pregnant women with a healthy fetus.

Exclusion criteria

Exclusion criteria: - Lack of informed consent from the study participant or (expectant) parents. - Diagnosed psychiatric illness of the study participant, currently undergoing treatment or about to undergo treatment.

Design outcomes

Primary

Measure	Time frame
The maternal emotional burden (measured by the parameters anxiety, depression and stress) at the following measuring points. 4 measuring points 1) Prenatal, diagnosis of CHD in fetal echocardiography during first trimester screening (12-14th gestational week). - maternal emotional burden measured with questionnaires -Spielberger State-Trait Anxiety Inventory (SSTAI) -Edinburgh Postnatal Depression Scale (EPDS) -Perceived Stress Scale (PSS) compared to pregnant women without fetal CHD diagnosis 2) prenatal, repetition of sonography ("organ ultrasound") (22-24th gestational week) - maternal emotional burden measured with questionnaires - "Spielberger State Anxiety Inventory" (SSAI) -EPDS -PSS - Socioeconomic status (SES) objective (educational level, income, employment status) - SES subjective ("MacArthur Scale of Subjective Social status") - Head circumference in fetuses with prenatal diagnosis of CHD compared to fetuses without diagnosis of CHD 3) Birth of the child with CHD 4) Cardiac surgery of the child with CHD - Maternal emotional burden measured with questionnaires -SSAI -EPDS -PSS	—

Measure

Time frame

The maternal emotional burden (measured by the parameters anxiety, depression and stress) at the following measuring points. 4 measuring points 1) Prenatal, diagnosis of CHD in fetal echocardiography during first trimester screening (12-14th gestational week). - maternal emotional burden measured with questionnaires -Spielberger State-Trait Anxiety Inventory (SSTAI) -Edinburgh Postnatal Depression Scale (EPDS) -Perceived Stress Scale (PSS) compared to pregnant women without fetal CHD diagnosis 2) prenatal, repetition of sonography ("organ ultrasound") (22-24th gestational week) - maternal emotional burden measured with questionnaires - "Spielberger State Anxiety Inventory" (SSAI) -EPDS -PSS - Socioeconomic status (SES) objective (educational level, income, employment status) - SES subjective ("MacArthur Scale of Subjective Social status") - Head circumference in fetuses with prenatal diagnosis of CHD compared to fetuses without diagnosis of CHD 3) Birth of the child with CHD 4) Cardiac surgery of the child with CHD - Maternal emotional burden measured with questionnaires -SSAI -EPDS -PSS

—

Secondary

Measure	Time frame
- Fetal and infant medical parameters: e.g., measurement parameters of sonography, pre- vs. postnatal diagnosis of CHD, perinatal course, clinical course - Association of maternal emotional burden situation with fetal medical parameters - mortality	—

Countries

Germany

Contacts

Public ContactLouise Teschemacher

Deutsches Herzzentrum Berlin Klinik für Angeborene Herzfehler/ Kinderkardiologie

Louise.Teschemacher@dhzc-charite.de+49 30 4593-2857

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026