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The Modulation of Motor-Cognitive Control by the Subthalamic Nucleus

The Modulation of Motor-Cognitive Control by the Subthalamic Nucleus

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00030402
Enrollment
30
Registered
2022-10-28
Start date
2023-03-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's disease

Interventions

Group 1: Unimodal intervention: Parkinson patients who are treated with deep brain stimulation (DBS) are asked to fill in questionnaires and to carry out computer-based experiments ON and OFF stimulat

Sponsors

Universität zu Köln
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: - Fluent in German - Between 18 and 80 years old - Capacity to consent and contract - Clinically established diagnosis of idiopathic Parkinson's syndrome - Existing bilateral implantation of subthalamic nucleus deep brain stimulation electrodes

Exclusion criteria

Exclusion criteria: - Instable, treatment-reliant psychiatric disease - Severe concomitant internal disease - Dementia - Withdrawal of consent

Design outcomes

Primary

MeasureTime frame
1) Connectivity of cortical networks involved in motor prediction and conflict resolution

Secondary

MeasureTime frame
2) Standardized scores of the motor prediction task (cue validity and trial-specific conflict level) 3) Standardized scores of the decision-making task (approach rate and approach latency for different losing probabilities) 4) Psychometric measures

Countries

Germany

Contacts

Public ContactAnnika Sauter

Klinik und Poliklinik für Neurologie, Klinikum der Universität zu Köln

annika.sauter@uk-koeln.de015227636593

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026