Comparison of three paradigms for deep brain stimulation programming in the nucleus subthalamicus in Parkinson's disease patients

Comparison of three paradigms for deep brain stimulation programming in the nucleus subthalamicus in Parkinson's disease patients - OptiSetSTN

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00030350

Enrollment

Registered

2023-03-24

Start date

2022-01-01

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G20.0

Interventions

Group 1: Clinical programming (monopolar review) Group 2: Anatomical programming Group 3: Electrophysiological programming

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Diagnosis of idiopathic Parkinson's disease, Implantation of deep brain stimulation with directional sensing electrodes in the subthalamic nucleus at least three months prior, Written informed consent for study participation, Complete preoperative imaging.

Exclusion criteria

Exclusion criteria: Concomitant diseases that may interfere with the focus of the study (especially severe underlying diseases, severe neurological or psychiatric concomitant diseases), lack of written consent to participate in the study

Design outcomes

Primary

Measure	Time frame
Differences in symptom control and time for programming (TFP) between different programming paradigms	—

Secondary

Measure	Time frame
Prespecified secondary endpoints were differences in total electrical energy delivered (TEED), rate of side effects, and stimulation parameters (i.e., amplitude, frequency, pulse width).	—

Countries

Germany

Contacts

Public ContactPhilipp Capetian

Universitätsklinik Würzburg

Capetian_P@ukw.de0931201223677

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026