healthy subjects with occasional digestive complaints (assessment via score system (Guyonnet et al.))
Conditions
Interventions
Group 1: bitter substance solution (plant extracts)
Group 2: menthol solution (placebo)
Sponsors
BitterPower GmbH
Eligibility
Sex/Gender
All
Age
35 Years to 60 Years
Inclusion criteria
Inclusion criteria: - age from 35 - 60 years - regular bowel movements - occasional, non-specific digestive complaints (without corresponding medical diagnosis), recorded by means of a screening questionnaire (Guyonnet et al., 2009); for study inclusion, an OSS between 8 and 16 or at least one complaint with OSS 4 is required - sufficient knowledge of German to understand the study documents and procedure
Exclusion criteria
Exclusion criteria: - BMI 29.9 kg/m² - acute illness with influence on gastrointestinal functions - medical diagnosis regarding digestive complaints - regular intake of drugs or dietary supplements with gastrointestinal effects/adverse effects - intake of drugs with potential interactions with the bitter substance solution or the menthol solution - use of antibiotics in the last four weeks prior to study entry - consumption of illegal substances - pregnancy or lactation - alcohol abuse (acute or in the medical history) - contraindications (e.g. allergies, intolerances) to the meals used in the study (standard meal and high flatulence meal), the bitter solution or the menthol solution
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| flatulence | — |
Secondary
| Measure | Time frame |
|---|---|
| fullness, cravings, overall digestion | — |
Countries
Germany
Contacts
Public ContactMartin Smollich
Institut für Ernährungsmedizin, Universität zu Lübeck
Outcome results
None listed