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Effects of prehabilitation before anterior cruciate ligament reconstruction on functional outcomes during rehabilitation - a randomized controlled trial

Effects of prehabilitation before anterior cruciate ligament reconstruction on functional outcomes during rehabilitation - a randomized controlled trial - PRAI (Preoperative Rehabilitation after ACL-Injury)

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00030312
Enrollment
114
Registered
2022-09-26
Start date
2023-04-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

S83.5 M23.61

Interventions

Group 1: Intervention group: guided, structured, criteria-based preoperative rehabilitation program adaptable to individual performance level. The prehabilitation program provides specific exercises
local muscle strength endurance training, increase of muscle cross-section, increase of neuromuscular strength qualities). The prehabilitation program consists of two training sessions of 60 minutes p

Sponsors

Deutsche Sporthochschule Köln
Lead Sponsor

Eligibility

Sex/Gender
All
Age
16 Years to 60 Years

Inclusion criteria

Inclusion criteria: • Patients (m/f/d) with acute ACL primary rupture with indication for surgical reconstruction • Planned ACL replacement surgery with autologous hamstring tendon or quadriceps tendon graft at Sana Dreifaltigkeitskrankenhaus Cologne, Germany • Patients are capable of giving consent, have full legal capacity and understand the nature, scope and significance of participation in the study

Exclusion criteria

Exclusion criteria: • Concomitant injuries with an intrinsic indication for surgery, that lead to a change in the treatment regimen • Surgery or injury to the knee joint in the last 5 years (both on the injured leg and on the contralateral leg) • Comorbidities that are counterindicated to an active exercise program (e.g. severe cardiovascular disease, neurological disease, ...). • Rheumatic underlying diseases • Pregnancy

Design outcomes

Primary

MeasureTime frame
Subjective knee function as assessed by the Knee Injury and Osteoarthritis Outcome Score (KOOS- total score), 1-7 days before reconstruction, on operative day (post-op), and 30, 60, 90, and 180 days post-op

Secondary

MeasureTime frame
• KOOS subscores (PAIN; SYMPTOMS; SPORT; ADL; QOL) • Mobility (range of motion in angular degrees, active and passive in flexion and extension of the knee joint, measured by means of a goniometer - by the test performers) • Control/ neuromuscular control (active stretch elevation) • Strength (quadriceps, hamstrings, plantarflexors; active heel lift, testing on isokinet) • functional test results (Y-Balance test and Counter Movement Jump incl. movement quality) • Activity level (Tegner score) • Ability to cope with everyday life and work • Return to sport Injury Scale (ACL-RSI)

Countries

Germany

Contacts

Public ContactRebecca Abel

Deutsche Sporthochschule Köln

r.abel@dshs-koeln.de+49 (0)221-4982-6165

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 9, 2026