no disease/health issue investigated
Conditions
Interventions
Group 1: The study will identify DNA methylation markers and highly variable DNA regions for tissue determination and trace causative assignment in a mixed trace and implement them in a model.
1) The
no complete individualizing DNA profile is generated in this process, therefore person identification considering the world population is not possible
4) Methods:
a. DNA quantification: real-time PCR
Sponsors
Universitätsklinikum Freiburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: no specific ones
Exclusion criteria
Exclusion criteria: biological relationship between participants For vaginal fluid and menstrual blood: no unprotected intercourse for 72 h. Otherwise no exclusion criteria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Differentiation/determination of biological origin of trace materials based on DNA methylation patterns at cell type-specific positions in the genome. | — |
Secondary
| Measure | Time frame |
|---|---|
| Assignment of biological origin to the corresponding trace causing person in a mixed trace using highly variable DNA regions. | — |
Countries
Germany
Contacts
Public ContactJana Naue
Universitätsklinikum FreiburgInstitut für Rechtsmedizin
Outcome results
None listed