Healthy volunteers
Conditions
Interventions
Group 1: 44 subjects (22 women, 22 men) will be examined. The study will be performed on an outpatient basis at the short-arm centrifuge and the tilting table of the Institute of Aerospace Medicine of
Sponsors
DLR Deutsches Zentrum für Luft- und Raumfahrt Institut für Luft- und Raumfahrtmedizin
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: - Male and female healthy volunteers between the ages of 20 and 50 years with A body mass index (BMI) of 20-26 kg/m2 and a height of 160-188 cm - No competitive athletes - Subjects willing and able to participate in the entire study - Successful completion of the inclusion examination - Present informed consent at the beginning of the study
Exclusion criteria
Exclusion criteria: - Drug or alcohol abuse (regular consumption of more than 20 - 30 g alcohol/day) - Heavy smoking - Obesity (BMI > 30) - Pregnancy (women) - Diabetes mellitus - Rheumatic disease - Muscle or joint diseases - Laser eye surgery - Herniated intervertebral disc - Taking psychotropic drugs and possibly other medications that may affect the experiments influence the experiments - claustrophobia - Heart disease or wearer of a pacemaker - Hypertension (values above 140/90 mmHg) or hypotension (values below 90/60 mmHg) - Pronounced orthostatic intolerance or vestibular balance disorders (kinetosis) - Renal disease (deviations from normal values for creatinine in plasma, normal value creatinine < 1.20 mg/dl *) - Thyroid dysfunction (deviations from normal values for TSH in plasma, normal values TSH 0.27 -4.20 mU/l*) (only in the case of anamnestic suspicion of dysfunction is a laboratory examination) - Anemia ( < Hb as normal values, normal value Hb men: 13.5 to 17.5 g/dl; normal values for women: 12.0 to 15.7 g/dl) * - Chronic back pain - Any other condition that, in the opinion of the investigator, makes the subject unsuitable for inclusion in for inclusion in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary Objective: To explore the effects of different strengths of gravitational stimuli on the perception of "upright" and "vertical" as a function of sex, and thereby improve our understanding of orientation perception in humans. | — |
Secondary
| Measure | Time frame |
|---|---|
| secondary objectives: (a) To explore sex differences in the influence of Earth's constant gravity on the effects of centrifugal force with respect to perception. b) To explore sex differences in the influence of otolith features on the perception of "vertical". | — |
Countries
Germany
Contacts
Public ContactTimo Frett
DLR - Deutsches Zentrum für Luft- und Raumfahrt e.V.Institut für Luft- und Raumfahrtmedizin
Outcome results
None listed