R49
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Teachers (max. 10 years full-time) or student teachers in good health between 21 and 39 years with symptoms of vocal fatigue. Control participants in good health between 21 and 39 years without symptoms of vocal fatigue.
Exclusion criteria
Exclusion criteria: • Lefthandedness • Smoking (past 5 years) • Known changes of the vocal folds (e.g., vocal fold nodules), vocal fold paralysis, surgeries on the larynx or thryoid or current organic or neurological changes of the vocal folds or vocal function per videoendoscopy and -stroboscopy of the larynx • History of voice therapy • Hoarseness • Respiratory illness, allergies (respiratory, silver), reflux or asthma at time of participation • Hearing disorder or hearing aids • Psychological, neurological or endocrinological disorders • Psychotropic or steorid medications • Body mass index > 30 • Indications against MRI such as metail parts in or on the body (e.g., permanent dental prostheses or braces, screws, prostheses, piercings or large tattoos • Nearsightedness > -5 diopters, if only glasses are worn • Claustrophobia • Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Vocal fatigue (raw scores, Vocal Fatigue Index, VFI Factor 1, Experiment 1 & 2) MRI activation in regions of interest (BOLD area 4p in mean %) as a function of speech tasks with and without stress induction (Experiment 1) Salivary cortisol (nmol/L) to determine stressresponders and nonresponders (Experiment 1) Suprahyoid and infrahyoid muscle activity (RMS, Experiment 1 & 2) Personality trait Social Potency (T-scores, Multidimensional Personality Questionnaire, MPQ, Experiment 1) Personality trait Stress Reaction (T-scores, Multidimensional Personality Questionnaire, MPQ, Experiment 1) Personality social anxiety (T-scores, Liebowitz Social Anxiety Scale, LSAS-fear, Experiment 1) | — |
Secondary
| Measure | Time frame |
|---|---|
| Vocal fatigue (raw data, Vocal Fatigue Index, VFI Factor 2 and 3, Experiment 1 & 2) Voice quality of life (raw data, Voice Handicap Index, VHI, Experiment 1 & 2) Vocal tract discomfort (raw data, Vokaltrakt-Beschwerden Skala, VTD, Experiment 1 & 2) Informal questionnaire on vocal health (raw data, Experiment 1) MRI activation in regions of interest (BOLD SMA, ACC, MCC, Amygdala, PAG in mean %) as a function of speech tasks with and without stress induction (Experiment 1) Personality trait Wellbeing, trait Social Closeness (T-scores, Multidimensional Personality Questionnaire, MPQ, Experiment 1) Personality social anxiety (T-scores, Liebowitz Social Anxiety Scale, LSAS-total, Experiment 1) Personality self-esteem (Rohdaten, Rosenberg self-esteem scale, Experiment 1) Behavioral inhibition and activation (raw data, BIS/BAS scales, BIS subscale, Experiment 1) Stress (T-scores, Trier Inventory of Chronic Stress, TICS, Experiment 1) Handedness (raw data, Edinburgh Händigkeitsfragebogen, EHI, Experiment 1) State positive and negative affect (Rohdaten, Positive and Negative Affect Schedule, PANAS, Experiment 1) Voice quality (relative fundamental frequency, RFF in ST; cepstral peak prominence in dB, Experiment 1 & 2) Perceived vocal effort (raw data, BORG-CR-10, Experiment 2) Cognitive effort (raw data, NASA-TLX, Experiment 2) | — |
Countries
Germany
Contacts
Universitätsklinikum Bonn