tumors in patients with a tumor predisposition syndrome sporadic tumors C00-C97 D00-D09 D10-D36 D37-D48
Conditions
Interventions
Group 1: Tumors developed in patients with tumor predisposition. Genetic and clinico-pathological characteristics.
Group 2: Sporadic tumors. Genetic and clinico-pathological characteristics.
Sponsors
Universitätsklinikum Augsburg, Medizinische Fakultät, Universität Augsburg
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: - Diagnosis of one or more tumor diseases (in tumor predisposition or sporadic) - Treatment in the University Hospital Augsburg or in one of the partner hospitals - Availability of sufficient tumor material (paraffin material and/or fresh tissue) so that, according to the pathologist in charge, sufficient tumor material is still available for any future diagnostic tests - Written consent from the patient to participate in the study
Exclusion criteria
Exclusion criteria: - Insufficient understanding of the German language
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Elucidation of the tumor evolution of tumors in the context of tumor predisposition and in comparison to sporadic tumors. | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) Description on the therapeutic response to (molecular) therapies as a function of tumor evolution. (2) Identification of genetic changes favoring metastasis. (3) Development of a system for predicting treatment response. (4) Development of a clinical course prediction system. | — |
Countries
Germany
Contacts
Public ContactMonika Golas
Medizinische Fakultät | Humangenetik, Universität Augsburg, Universitätsklinikum Augsburg
Outcome results
None listed