G20.0
Conditions
Interventions
Group 1: The following tests are carried out once for people with PD:
UPDRSIII
Hoehn & Yahr
Timed up and go test
6 minute walk test
treadmill analysis
In addition, the following questionnaires are f
Sponsors
Universitätsmedizin der Johannes Gutenberg-Universität Mainz
Eligibility
Sex/Gender
All
Age
40 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria for IPS patients - idiopathic parkinsonian syndrome (according to British brain bank criteria: L-dopa sensitivity of at least 50%) - Hoehn and Yahr Stage = 2.5. - Fluctuations and/or dyskinesias for no longer than 3 years. - written declaration of consent. - Age (40-70 years) Inclusion criteria for healthy subjects - Only healthy people without significant previous illnesses are examined (e.g. neurological, psychiatric or orthopedic illnesses that suggest an influence on movement behavior, gait security and balance. These include e.g. hemiplegia, polyneuropathy, multiple sclerosis). - Age (40-70 years)
Exclusion criteria
Exclusion criteria: - Fall history: > 1 fall in the last 12 months, only allow 1 fall in the last 12 months if other tests have not shown any abnormalities (NFOGQ = 0; UPDRSIII Item 3.10 = 0; UPDRSIII Item 3.11 = 0; TUG =2 - UPDRSIII-Item 3.11 (Freezing): >=2 - UPDRSIII item 3.13 (posture): >=2 - NFOGQ item 5. If item 5 is rated 2, an additional item 6 is considered. The patient is excluded if item 6 is scored >= 2 - Occurrence of dyskinesia - 6MWT: 30 - Large scars or tattoos on the back
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| - Height of the amplitude and time of occurrence of the pelvis and the vertebral body position maxima during a standardized gait cycle (SGC) in the rotational movement (vertebral spine movement in the transverse plane in 17 movement segments) - Progression diagram of the individual vertebral bodies in the SGC | — |
Secondary
| Measure | Time frame |
|---|---|
| - Amplitude, frequency and asymmetry of arm accelerometers - Amplitude, frequency and asymmetry of electrical muscle activity (EMG) - UPDRSIII total score - UPDRSIII bradykinesia, rigidity, gait subscores - Timed-up-and-Go (TUG) test score - Distance of the 6 Minute Walking Test (6MWT) - Overall score of the New Freezing of Gait Questionnaire | — |
Countries
Germany
Contacts
Public ContactManuel Bange
Universitätsmedizin der Johannes Gutenberg-Universität Mainz
Outcome results
None listed