I63 I61
Conditions
Interventions
Group 1: Registry: Patients with acute stroke requiring rehabilitation will be clinically assessed at 7 days after stroke (if included in the acute hospital), and at 28 days, 3, 6, 12, and 24 months a
Sponsors
Charité Campus Charité Mitte
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. male or female adult:r = 18 years at the time of study inclusion. 2. acute stroke (ischemic or intracerebral hemorrhagic) confirmed by computed tomography (CT) or magnetic resonance imaging (MRI) image morphology 3. inclusion in the study within = 9 days after stroke (inclusion in an acute care hospital) or within = 35 days after stroke (inclusion in a rehabilitation hospital/geriatric ward) 4. neurological or geriatric rehabilitation (outpatient or inpatient) planned or recommended.
Exclusion criteria
Exclusion criteria: 1. no neurological or geriatric rehabilitation (outpatient or inpatient) planned. 2. intracranial hemorrhage primary in the context of a subarachnoid hemorrhage, subdural or epidural hematoma (small, concomitant portions in primary ICB are not an exclusion criterion) 3. post-stroke according to diagnosis list (clinically silent strokes not known or diagnosed prior to stay are not exclusion criteria) 4. invasive long-term ventilation at the time of study inclusion 5.Life expectancy before stroke 30 minutes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| RECOVER-S aims to examine stroke rehabilitation in Germany using a multicentric- and biomarker-based approach to provide a reliable depiction on the standard of care in stroke stroke rehabilitation. This registry-based cohort study has the following goals: 1. To evaluate the association between stroke rehabilitation therapies and long-term functional and subjective outcome with regards to timing, intensity, duration, dosing and amount of stroke rehabilitation. Hypothesis to goal 1: There is an interindividual difference in the subjective and functional recovery of stroke patients after 6 months, that depends on the type, timing, intensity, duration, dosing and amount of stroke rehabiliation. This hypothesis will be tested using the following endpoints: Primary Endpoints: 1. Activities in daily living (assessed by the Barthel-Index) at six months after stroke 2. Health-related quality of life (assessed by the EQ-5D-5L) at six months after stroke | — |
Secondary
| Measure | Time frame |
|---|---|
| Key Secondary Endpoints: 1. Safety (all-cause mortality, combined cardiovascular events (stroke, myocardial infarction), re-hospitalization, frequency and severity of falls) 2. Clinical scores (modified Rankin Scale (mRS), National institutes of health stroke scale (NIHSS)) 3. Functional Scores (e.g., volitional grip movement) 4. Quality of aftercare 5. Activities in daily living (assessed by the Barthel-Index)at 12 and 24 months after stroke 6. Health-related quality of life (assessed by the EQ-5D-5L)at 12 and 24 months after stroke | — |
Countries
Germany
Contacts
Public ContactAlexander Heinrich Nave
Charité Universitätsmedizin Berlin Klinik für Neurologie
Outcome results
None listed