Endometriosis in pregnancy - effect on the risk of pregnancy and birth complications

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00029933

Enrollment

512

Registered

2022-08-26

Start date

2022-01-15

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

N80 O43 O14 P07

Interventions

Group 1: Pregnant women with endometriosis are monitored for pregnancy complications and asked to complete a questionnaire before delivery about their history and counselling needs during pregnancy. G

Eligibility

Sex/Gender

Female

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Pregnant women with a singleton pregnancy; birth at the Charité Campi Mitte, Virchow Klinikum or DRK Westend; ability to contract, existence of a declaration of consent; for case patients: anamnestically reported and documented endometriosis.

Exclusion criteria

Exclusion criteria: Pregnant women with severe maternal diseases; multiple pregnancies; abnormalities in the extended basic screening; uterine malformations. basic screening; uterine malformations; previous operations on the uterus with opening of the cavity; inability to give consent, lack of informed consent.

Design outcomes

Primary

Measure	Time frame
(WHAT) The occurrence of prematurity, preeclampsia and pathological conditions of the placenta (placenta praevia, accreta, percreta, increta; insertio velamentosa, vasa praevia) during pregnancy is detected (WHEN) at the regular screening appointments and at the time of birth. (HOW) with the usual measurement procedure of the respective pathology (calculation of the date of birth by means of ultrasound diagnostics; urine diagnostics, blood count incl. sFlt/PlGF and blood pressure measurement in case of suspected preeclampsia or HELLP syndrome; ultrasound diagnostics with determination of the placental and umbilical cord location) and recorded in the Viewpoint documentation program. The examination and documentation is carried out by the attending physician present at the time of birth.	—

Measure

Time frame

(WHAT) The occurrence of prematurity, preeclampsia and pathological conditions of the placenta (placenta praevia, accreta, percreta, increta; insertio velamentosa, vasa praevia) during pregnancy is detected (WHEN) at the regular screening appointments and at the time of birth. (HOW) with the usual measurement procedure of the respective pathology (calculation of the date of birth by means of ultrasound diagnostics; urine diagnostics, blood count incl. sFlt/PlGF and blood pressure measurement in case of suspected preeclampsia or HELLP syndrome; ultrasound diagnostics with determination of the placental and umbilical cord location) and recorded in the Viewpoint documentation program. The examination and documentation is carried out by the attending physician present at the time of birth.

—

Secondary

Measure	Time frame
Desire for counselling during pregnancy, collected at the time of study inclusion before birth by questionnaire.	—

Countries

Germany

Contacts

Public ContactGreta Sophie Ebeling

Klinik fu¨r GynäkologieCharité-Universitätsmedizin BerlinRudolf Virchow Klinikum

greta-sophie.ebeling@charite.de+49 30 450 564 901

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026