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Positivity Training: Effects of a Bias Modification Training on Emotion Processing in Major Depression and healthy Controls

Positivity Training: Effects of a Bias Modification Training on Emotion Processing in Major Depression and healthy Controls - Positive CBM

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00029756
Enrollment
240
Registered
2022-08-16
Start date
2023-01-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

DSM-V: Major Depression F32

Interventions

Group 1: Experimental training of positive emotion stimuli in people wiht depression. Using a dot-probe design, participants see two pictures with positive and neutral valence. In the experimental tra

Sponsors

Klinik für Psychiatrie, Psychotherapie und Psychosomatik., Uniklnik RWTH Aachen
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Major Depression: DSM-V: 32.0/1/2/4/5/8/9; DSM-V: 33.0/1/2/4/5/9

Exclusion criteria

Exclusion criteria: Pregnancy, Symtoms of psychosis or mania. Substance dependency (apart from Nicotine). Neurological disorders and diseases affecting the brain: hypo- or hyperthyroidism, diabetes (HBA1c > 7,5, stroke).

Design outcomes

Primary

MeasureTime frame
Change in Amplitude (µV) of the "Early Processing Negativity" (EPN) derived from EEG in response to picture stimuli with posivie emotion valence from pre- to post intevention assessments.

Secondary

MeasureTime frame
Prä/post intervention change in Late Positive Potential Evoked Response Potential Amplitude (µV) (LPP), EEG microstates derived from EEG, Montgomery Asberg Rating Scale rating score (MADRS) Hamilton Depresson Rating Scale rating score (HAMD) Beck Depression Inventory questionnaire score (BDI-II) State-Traint Anxiety Inventory questionnaire score (STAI)

Countries

Germany

Contacts

Public ContactA. S. Lemmrich

Klinik für Psychiatrie, Psychotherapie und Psychosomatik

ps-Studienkoordination@ukaachen.de+49 241 80-89633

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Sep 3, 2026