G62
Conditions
Interventions
Group 1: Intervention group (group 1): Rhythmic embrocation (RE) according to Wegman/ Hauschka with a base oil (e.g.: almond oil) on the feet, 3 applications within a 14-day period, interval between t
Sponsors
Medizinische Hochschule Hannover (MHH), Klinik für Strahlentherapie, OE 8240
Eligibility
Sex/Gender
All
Age
18 Years to 95 Years
Inclusion criteria
Inclusion criteria: 18-95 years, diagnosis of oncologic disease and symptoms of chemotherapy-induced polyneuropathy (CIPN), patient consent, patients have received at least one course of platinum-, taxane-, or vincaloid-based chemotherapy, proteasome inhibitor, or thalidomide/lenalidomide/pomalidomide therapy, indication of at least. 4 points on the Numeric Rating Scale (NRS) for pain, cramps, tingling, or numbness in the feet (score: =4/10), platelet count greater than 100,000/µL
Exclusion criteria
Exclusion criteria: According to the inclusion criteria, patients with polyneuropathy already before oncological system therapy, platelets<100,000/µl. Psychological restrictions (lack of capacity to consent), which do not allow participation in the study. Interventions such as massages/ rubs with or without oils during the study period. Infections and/or open wounds on the feet, coagulopathies, allergy to the base oil, other neuropathies such as diabetic polyneuropathy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary endpoint: Change in pain on the 10-item NRS compared before the start of the 1st application (RE) to 24 hours after the 3rd treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints: NRS 24 hours, at 2 and 4 weeks after 1st RE, symptom assessment of polyneuropathy (EORTC QLQ-CIPN20) 2 and 4 weeks after initiation of RE. | — |
Countries
Germany
Contacts
Public ContactDiana Steinmann
Medizinische Hochschule Hannover (MHH), Klinik für Strahlentherapie, OE 8240
Outcome results
None listed