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Evaluation of the remineralization behavior of human enamel in-situ using the in-vitro standard

Evaluation of the remineralization behavior of human enamel in-situ using the in-vitro standard

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00029718
Enrollment
8
Registered
2022-07-20
Start date
2022-10-08
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K02.0

Interventions

Group 1: Use of fluoridated toothpaste 1. At the beginning an impression of the mandible is made for each subject and a mandibular splint with four embedded human enamel specimen will be made for eac

Sponsors

Zahnarztpraxis
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - low caries risk - Patients are willing and able to understand all study-related procedures and follow instructions

Exclusion criteria

Exclusion criteria: - Patients with: - high caries risk - removable dentures in the lower jaw - multibracket appliance - recent dental surgery - known allergies/hypersensitivities to the materials used - a currently present periodontal disease - signs of tooth erosion (excessive drinking of acidic beverages, reflux) - Diseases or concomitant medication that impair salivary flow or cause a dry mouth - Pregnant/breastfeeding women - Patient refuses the use of fluoride toothpaste - Patient refuses short-term use of fluoride-free toothpaste

Design outcomes

Primary

MeasureTime frame
Comparison of the relative gray value (relDelta A [%]) between de- and remineralized areas within a tooth enamel sample and in a group comparison.

Secondary

MeasureTime frame
Comparison of the relative gray value (relDelta A [%]) between de- and remineralized areas between in-situ and in-vitro samples.

Countries

Germany

Contacts

Public ContactAnahita Jablonski-Momeni

Philipps-Universität Marburg, Medizinisches Zentrum für ZMK, Abteilung für Kieferorthopädie

momeni@staff.uni-marburg.de06421-5863221

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026