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Comprehensive characterization of alcohol-induced postural instability and walking ataxia in healthy participants: a new model to mimic sensory and cerebellar ataxia?

Comprehensive characterization of alcohol-induced postural instability and walking ataxia in healthy participants: a new model to mimic sensory and cerebellar ataxia? - ALCATAX

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00029699
Enrollment
20
Registered
2022-07-19
Start date
2022-09-23
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ataxic gait R27.0

Interventions

Group 1: Initially, balance tests, gait analysis at different speeds and a movement sequence with the arms are performed. Then an individually determined amount of alcohol is ingested and the initial

Sponsors

Zentrum für Schwindel und GleichgewichtsstörungenUniversitätsspital Zürich
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: - Signed informed consent - absence of exclusion criteria

Exclusion criteria

Exclusion criteria: - Alcohol dependence or intolerance - pregnant or breastfeeding women - every orthopedic, neurological or systemic disease affecting walking or postural balance

Design outcomes

Primary

MeasureTime frame
Change in gait parameters that are characteristic for ataxic disorders (variability in step length and trunk sway) as a function of gait speed under the influence of alcohol.

Secondary

MeasureTime frame
- Change in the subscores of condition five and six (postural control via vestibular/cerebellar networks) in the sensory organization test (SOT) under the effect of alcohol. - Change in the adaptation to postural perturbations under the effect of alcohol. - Change in the accuracy of arm movements in the finger-to-nose test under the effect of alcohol.

Countries

Switzerland

Contacts

Public ContactYulia Valko

Klinik für NeurologieUniversitätsspital Zürich

yulia.valko@usz.ch+41 44 255 55 50

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026