Healthy volunteers
Conditions
Interventions
Group 1: Sixteen subjects (8 women, 8 men) will be studied. Subjects with experience in centrifugation
in centrifugation are preferred in order to avoid failures due to medically induced experiment
a
Sponsors
DLR Deutsches Zentrum für Luft- und Raumfahrt Institut für Luft- und Raumfahrtmedizin
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: - Male and female healthy volunteers between the ages of 20 and 50 years with A body mass index (BMI) of 20-26 kg/m2 and a height of 160-188 cm - No competitive athletes - Normal vision or vision corrected to normal with the aid of contact lenses/glasses Visual acuity - Subjects willing and able to participate in the entire study - Successful completion of the inclusion examination - Present informed consent at the beginning of the study
Exclusion criteria
Exclusion criteria: - Drug or alcohol abuse (regular consumption of more than 20 - 30 g alcohol/day) - Heavy smoking - Obesity (BMI > 30) - Pregnancy (women) - Diabetes mellitus - Rheumatic disease - Muscle or joint diseases - Laser eye surgery - Color vision deficiency - Herniated intervertebral disc - Taking psychotropic drugs and possibly other medications that may affect the experiments influence the experiments - claustrophobia - Heart disease or wearer of a pacemaker - Hypertension (values above 140/90 mmHg) or hypotension (values below 90/60 mmHg) - Pronounced orthostatic intolerance or vestibular balance disorders (kinetosis) - Renal disease (deviations from normal values for creatinine in plasma, normal value creatinine < 1.20 mg/dl *) - Thyroid dysfunction (deviations from normal values for TSH in plasma, normal values TSH 0.27 -4.20 mU/l*) (only in the case of anamnestic suspicion of dysfunction is a laboratory examination) - Anemia ( < Hb as normal values, normal value Hb men: 13.5 to 17.5 g/dl; normal values for women: 12.0 to 15.7 g/dl) * - Chronic back pain - Any other condition that, in the opinion of the investigator, makes the subject unsuitable for inclusion in for inclusion in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Investigate the effects of different strengths of gravitational stimuli on the perception of "upright" and "vertical" and thereby improve our understanding of orientation perception in humans as well as quantification of the threshold above which a perceptible contribution of gravity to the determination of the PU can be detected. | — |
Secondary
| Measure | Time frame |
|---|---|
| a) Investigation of the influence of the constant gravity of the earth on the effects of centrifugal force with respect to perception. b) Exploring the effects of different strengths of gravitational stimuli on cerebral cortex activity. c) Exploration of the influence of otolith features on the perception of "vertical". d) Exploring the influence of otolith features in combination with consistent visual features on the perception of "vertical" e) Exploration of the inconsistencies of the results in the range around 0.06g. | — |
Countries
Germany
Contacts
Public ContactAlexandra Noppe
DLR - Deutsches Zentrum für Luft- und Raumfahrt e.V.Institut für Luft- und Raumfahrtmedizin
Outcome results
None listed