I26.0
Conditions
Interventions
Group 1: Prior to the treatment with EKOS Lysis Catheter blood is taken and testet for several parameters regarding coagulation (eg TEG, clotting, Quick, PTT, fibrinogen and others) Further echocardio
Sponsors
Uniklinik Freiburg
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: age 18 years or older Acute Pulmonary Embolism Right ventricular dysfunction Meeting criteria for intermediate risk Pulmonary embolism according to ESC Guidelines
Exclusion criteria
Exclusion criteria: Known significant bleeding risk Administration of thrombolytic agents within the previous 4 days Vena cava filter insertion or pulmonary thrombectomy within the previous 4 days Previous enrolment in this study Any other condition that the investigator feels would place the patient at increased risk if the investigational therapy is initiate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| At the beginnen and 24-96h after treatment the ratio of the diameters of the right and left ventricle is assessed via echocardiografie. Primary outcome is the change of RV/LV ratio under therapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| In hospital mortality Bleeding Haemodynamic stability Exploratory markers Development of CTEPH | — |
Countries
Germany
Contacts
Public ContactMarius Wessinger
Uniklinik Freiburg, Klinik für Kardiologie und Angiologie
Outcome results
None listed