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Assessment of dynamic cerebral autoregulation in near-infrared-spectroscopy using short-distance channels: a feasibility study in acute ischemic stroke patients

Assessment of dynamic cerebral autoregulation in near-infrared-spectroscopy using short-distance channels: a feasibility study in acute ischemic stroke patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00029613
Enrollment
54
Registered
2022-07-26
Start date
2020-02-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute ischaemic stroke I63.9

Interventions

Group 1: Group: acute ischaemic stroke - change in head of bed 30° - 0° - 30° Group 2: Group: healthy controls - change in head of bed 30° - 0° - 30°

Sponsors

Universitätsklinik für Neurologie Oldenburg
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Age at least 18 years Stroke-typical clinic in the sense of an acute, focal neurological deficit with sudden onset Ischemic cerebral infarction demonstrated on imaging Measurement within < 48 hours after infarct event

Exclusion criteria

Exclusion criteria: Presence of one or more of the following conditions: Internal carotid artery (ACI) stenosis with > 40% occlusion as defined by NASCET [143]. Disease with severe autonomic nervous system dysfunction. subdural hematoma or subarachnoid hemorrhage Stay in intensive care unit within 48 hours of onset of focal neurologic deficit Person incapable of informed consent and no consent from a legal guardian Insufficient knowledge of the German language to fully comprehend and assess participant information and no adequate translation possible.

Design outcomes

Primary

MeasureTime frame
Gain and phase shift of (V)LFO, recorded via near infrared spectrosocopy

Secondary

MeasureTime frame
Clinical applicability in the sense of a feasibility study

Countries

Germany

Contacts

Public ContactKarsten Witt

Universitätsklinik für Neurologie Oldenburg

karsten.witt@uni-oldenburg.de+49 (0)441 236-649

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026