balanced anesthesia inhalation anesthesia
Conditions
Interventions
Group 1: Surgical patients receiving general anesthesia at RWTH Aachen University and other interested German hospitals
Sponsors
Klinik für Anästhesiologie, Uniklinikum RWTH Aachen
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: • =18 years • ASAI-II • MET=4 • General anesthesia with sevoflurane • Elective surgery with intubation
Exclusion criteria
Exclusion criteria: • Not willing to participate • not able to provide informed consent • pregnancy • BMI=30kg/m2 and <18kg/m2 • severe respiratory disease • single lung ventilation • cardiac and thoracic surgery • extracorporeal membrane oxygenation • emergency surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sevoflurane consumption in ml during induction of anesthesia (cumulative amount in the first 7 minutes after opening of vaporizer 1) | — |
Secondary
| Measure | Time frame |
|---|---|
| - Sevoflurane consumption in ml during maintenance - Ventilation settings: Fresh gas flow, Vaporizer setting, Fraction of inspiratory and expiratory oxygen, endtidal sevoflurane concentration - minimal alveolar concentration (MAC) - Ventilation complications: laryngospasm, bronchospasm - Narcotic depth: neuromonitoring, need for additional propofol bolus - Hemodynamic stability: mean arterial blood pressure, need for vasopressors, bradycardia/tachycardia - Economic efficiency: Cost savings - Sustainability: CO2 equivalents | — |
Countries
Germany
Outcome results
None listed