Pharmacokinetic interactions between antiepileptic drugs (AED) and direct oral anticoagulants (DOAC).

Pharmacokinetic interactions between antiepileptic drugs (AED) and direct oral anticoagulants (DOAC). - AED-DOAC

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00029398

Enrollment

Registered

2022-07-20

Start date

2022-08-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G40.9 I48.9

Interventions

Group 1: patients with existing comedication of DOAC and AED: documentation of clinical data and one-time measurement of substance-specific laboratory parameters at the time of study enrollment. Group

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: - patients with existing comedication of DOAC and AED - patients taking DOAC with new indication for AED - patients taking DOAC without AED treatment - all approved AEDs in monotherapy - all approved DOACs

Exclusion criteria

Exclusion criteria: - patients with legal guardianship - polytherapy of AED

Design outcomes

Primary

Measure	Time frame
Plasma concentrations of DOACs	—

Countries

Germany

Contacts

Public ContactSophie Schlabitz

Charité – Universitätsmedizin Berlin, Klinik für Neurologie, Klinische und Experimentelle Epileptologie

Sophie.Schlabitz@charite.de030450560003

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026