Children and adolescents receiving contrast-enhanced MRI for clinical indication.
Conditions
Interventions
Group 1: Patients will have additional MR sequences (REACT VANE sequence and T1-FFE contrast angiography, if applicable) measured as part of their clinically indicated contrast-enhanced MRI. This will
Sponsors
Universitätsklinikum Tübingen
Eligibility
Sex/Gender
All
Age
3 Months to 20 Years
Inclusion criteria
Inclusion criteria: • Male and female patients. • Referral from pediatrics with a clinical indication for a contrast-enhanced MRI scan. • Examination on the Philips Ingenia 1.5 Tesla. • Presence of all necessary laboratory parameters (creatinine/GFR according to internal guidelines of the UKT). • No need for anesthesia for the MRI examination. • Written consent for the study from the patient and/or guardian.
Exclusion criteria
Exclusion criteria: • All MR-relevant contraindications. • Contraindication to contrast agent administration (gadolinium). • Need for anesthesia for MRI examination. • Patient non-compliance for MRI examination or for study-related extension of MRI examination time. • No written informed consent for the study from the patient and/or guardian.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To establish a qualitative and quantitative comparison based on various criteria (resolution and diameters of co-imaged vessels as well as detection of vascular anomalies and normovariances) to evaluate the image quality of the study-related newly implemented sequence (REACT VANE) in comparison to standard MR angiography or contrast dynamics. | — |
Secondary
| Measure | Time frame |
|---|---|
| • Comparative determination of occurring motion artifacts. • Determination of the rate of examinations with potentially saved contrast medium (no significant difference between contrast medium-free and contrast medium-enhanced angiography). | — |
Countries
Germany
Contacts
Public ContactJakob Spogis
Universitätsklinikum Tübingen, Radiologie, Diagnostische & Interventionelle Radiologie
Outcome results
None listed