Alzheimers disease Ssyndrome
Conditions
Interventions
Group 1: Patients with Alzheimers disease syndrome
Group 2: Healthy controls
Sponsors
Uniklinik Köln, Klinik für Nuklearmedizin
Eligibility
Sex/Gender
All
Age
50 Years to No maximum
Inclusion criteria
Inclusion criteria: For healthy controls: 1. Age > 50 years 2. Subjectively unimpaired cognitive performance For patient group: 1. Age > 50 years 2. Alzheimer’s clinical syndrome according to NIA-AA criteria
Exclusion criteria
Exclusion criteria: For healthy controls: 1. No history of chronic neurological diseases, such as PD, MS, Stroke etc. 2. Known clinically relevant motor deficit For patient group: 1. Fulfils criteria for other forms of dementia than of the Alzheimer’s disease type 2. Other disorders potentially responsible for cognitive decline or motor deficits (e.g., cerebrovascular disorders, Parkinson’s disease) 3. Lack of ability to provide informed consent
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Apraxia symptomes in patients with Alzheimer's disease syndrome will be assessed using the KAS (Kölner Apraxie Screening) and extensive motor testing. Prevalence of apraxia symptomes will be calculated. | — |
Secondary
| Measure | Time frame |
|---|---|
| Molecular and neurophysiological basis of apraxia in Alzheimer's disease syndrome | — |
Countries
Germany
Contacts
Public ContactElena Jäger
Uniklinik Köln, Klinik für Nuklearmedizin
Outcome results
None listed