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Comparison of controlled ventilation and non-ventilation during extracorporeal membrane oxygenation (ECMO): Respiratory physiological effects

Comparison of controlled ventilation and non-ventilation during extracorporeal membrane oxygenation (ECMO): Respiratory physiological effects

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
DRKS
Registry ID
DRKS00029317
Enrollment
12
Registered
2022-06-15
Start date
2022-11-15
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

J80.0 J80.03

Interventions

Group 1: Patients in ARDS with ECMO therapy are mechanically ventilated for one hour instead of the usual apnea tolerance. From ten minutes before to one hour after the ventilation phase respiratory d

Sponsors

Universitätsklinikum Freiburg, Klinik für Anästhesiologie und Intensivtherapie
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age = 18 years Severe ARDS and treatment with veno-venous ECMO

Exclusion criteria

Exclusion criteria: Age NYHA 2, contraindications to EIT measurements (active implants, eg. pacemakers, cardioverters, skin disease or injury to the skin in the position of the EIT electrode-belt), BMI = 35 kg/m^2.

Design outcomes

Primary

MeasureTime frame
Relative end-expiratory lung volume, regional ventilation/perfusion ratio (V/Q).

Secondary

MeasureTime frame
Compliance of the respiratory system, homogeneity or distribution in regional ventilation (indicated by ratio of dorsal to ventral ventilation), PaO2, PaCO2, etCO2, FiO2, FeO2, airway pressure, respiratory gas flow, vital signs.

Countries

Germany

Contacts

Public ContactStefan Schumann

Universitätsklinikum Freiburg, Klinik für Anästhesiologie und Intensivtherapie

stefan.schumann@uniklinik-freiburg.de0761/270-23290

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026