A retrospective analysis of local lysis therapy for central, intermediate-high-risk pulmonary embolism

A retrospective analysis of local lysis therapy for central, intermediate-high-risk pulmonary embolism - RetroLoLyLu

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00029299

Enrollment

Registered

2022-06-15

Start date

2022-06-13

Completion date

Unknown

Last updated

2025-10-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

I26

Interventions

Group 1: Patients treated as inpatients with a diagnosed, central, intermediate high-risk pulmonary embolism at the Elblandklinikum Radebeul in the years 2017-2021

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: age >18 years; Unilateral or bilateral central, intermediate high-risk pulmonary embolism (definition according to ESC guideline 2019); Treatment in the Elblandklinikum Radebeul; Performed locoregional lysis of the pulmonary arteries with side hole lysis catheter; Patient consent to data processing

Exclusion criteria

Exclusion criteria: Age < 18 years

Design outcomes

Primary

Measure	Time frame
Composite endpoint of mortality, minor bleeding (not requiring transfusion) and major bleeding (requiring transfusion/requiring surgery)	—

Secondary

Measure	Time frame
Reduction of right ventricular stress, reduction of resting heart rate, improvement of peripheral oxygen saturation at rest	—

Countries

Germany

Contacts

Public ContactRainer Waßmer

Elblandklinikum RadebeulInterdisziplinäres Gefäßzentrum/Angiologie

Rainer.Wassmer@elblandkliniken.de03518334317

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026