G47.8 F06.7
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - Healthy participants of female, male or another gender between the ages of 40 and 85 years - after written consent
Exclusion criteria
Exclusion criteria: presence of a disease which could potentially impair the motor function or responsiveness, including the following: - neurological diseases: o history of stroke o history of cerebral haemorrhage o multiple sclerosis o history of meningitis or encephalitis o epilepsy o chronic headache or migraine (duration > 3 months, minimum of 15 days per month) o brain tumour o pronounced polyneuropathy with impairment of the upper extremities o neurodegenerative disease Parkinson's disease (incl. prodromal stages such as REM sleep behaviour disorder) Alzheimer's disease or a different type of dementia; Cut-off-score for MoCA = 23 points - presentation of a presently treated, oncological disease - severe sight disorder that cannot be adjusted for by use of a visual aid - presentation of a cardiological disease with impaired left or right ventricular pump function (NYHA III-IV) - presentation of an orthopedic disease/injury/dysfunction that is ongoing or was present in the last 6 months, impairs the grip function and affects one or multiple of the following localisations: o upper extremity (hand, finger, wrist, elbow) o cervical spine o thoracis spine - centrally acting medication that possibly impairs the motor function or responsiveness
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcomes are the results of the falling stick test, namely the distance (in centimeters) the stick drops until it is touched/caught/stopped from falling and the grip force when the stick is caught/stopped from falling. The outcomes are measured during the study visit (after collection of covariates) using the NeuroMex system by Saniva Diagnostics GmbH. | — |
Secondary
| Measure | Time frame |
|---|---|
| No other outcomes, but covariates are measured: cognitive impairment (by use of the Montreal Cognitive Assessment), age, gender, handedness, height, weight, body mass index, education, vocational education, nationality, migration status and country of origin. | — |
Countries
Germany
Contacts
Hans Berger Klinik für Neurologie, Universitätsklinikum Jena