Healthy participants
Conditions
Interventions
Group 1: foods visit 1
volunteer01 combination 1
volunteer02 zuccini
volunteer03 carrot
volunteer04 combination 3
volunteer05 spinach
volunteer06 zuccini
volunteer07 kiwi
volunteer08 peas
volunteer09 spinach
volunteer10 peas
volunteer11 cucumber
volunteer12 kiwi
volunteer13 combination 1
volunteer14 combination 2
volunteer15 green beans
combination 1 = salat of fruits (blueberries, strawberries, orange, banana, grape, pear, apple) and coffee
combination 2 = salat white cabbage, red cabbage, broccoli, cauliflower, kohlrabi, onion, olive oil, tomato, mushrooms, potato, walnuts and red wine
combination 3 = wholegrain crispbreads, dark chocolate and black tea
Group 2: foods visit 2
volunteer01 cucumber
Sponsors
Max Rubner-Institut; Bundesforschungsinstitut für Ernährung und Lebensmittel
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: - Healthy women and men (18-40 years) - BMI 18.5 - 30 kg/m2 - Good health status - Written informed consent to participate in the study - No medical conditions affecting nutrient absorption, digestive function, metabolism or excretion - Non-smoker - No regular use of medication (except hormonal contraceptives) - No intake of antibiotics in the previous 6 months - No intake of nutritional supplements in the preceding 4 weeks - No pregnancy or lactation period - No allergy/ intolerance to food or ingredients of the test meals
Exclusion criteria
Exclusion criteria: - Need to take certain medications during the trial period; the assessment is made by the study physician - Occurrence of unacceptable adverse events - Withdrawal of consent to participate in the study - Non-compliance with the instructions in the study protocol (including hygiene measures) the hygiene measures)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analysis of the specific increase or specific occurrence of metabolites/marker candidates in urine derived from the tested plant food after a single consumption of the test food compared to the fasting urine sample using untargeted LC-MS-based metabolomics methods. | — |
Secondary
| Measure | Time frame |
|---|---|
| Determination of the expected concentration range for the selected marker candidates in the urine of participants, and, if possible, identification of new marker candidates in the urine for the consumed foods using LC-MS based methods. | — |
Countries
Germany
Contacts
Public ContactMaria Herrmann
Max-Rubner-Institut Bundesforschungsinstitut für Ernährung und Lebensmittel
Outcome results
None listed