E11
Conditions
Interventions
Group 1: Magnesium-rich mineral water (124mg/L), 2-2.5 litres per day, for 12 weeks
Group 2: Magnesium-rich mineral water (101mg/L), 2-2.5 litres per day, for 12 weeks
Group 3: Magnesium-rich mineral
Sponsors
Gottfried Wilhelm-Leibniz-Universität Hannover Institut für Lebensmittelwissenschaft und Humanernährung
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: Diabetes type 2 diagnosis; BMI between 20 and 35; Willingness to consume 2-2.5 liters of mineral water daily for 12 weeks.
Exclusion criteria
Exclusion criteria: Insulin therapy; recent (<2 months) change in medications or supplements affecting blood glucose; diagnosed blood coagulation disorders as well as taking anticoagulant medications such as Marcumar (except ASA); participation in another clinical trial within the last 30 days
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HbA1c levels after 12 weeks of intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| Except for size, all parameters are recorded at baseline and after 12 weeks. Blood: Fasting glucose, Fasting insulin, HOMA index, Inflammatory parameters (C-Peptide/hsCRP), Magnesium, Calcium, 25-Vitamin D, TG, LDL, HDL, Total cholesterol, Blood count (in particular Neutrophil-Lymphocyte ratio and Platelet-Lymphocyte ratio), Safety parameters (creatinine, GOT, GPT, GGT); Urine: Magnesium, Calcium, Kalium, Creatinine, Uric acid; Questionnaires: 3-day food record, Short Form of Health (SF-36), Single-item sleep quality scale (SQS), Other parameters: Blood pressure, pulse, Anthropometric measures: weight, height, BMI, waist circumference, Arterial stiffness via carotid-femoral pulse wave velocity, | — |
Countries
Germany
Contacts
Public ContactJulius Schuster
Leibniz Universität Hannover, Institut für Lebensmittelwissenschaft und Humanernährung
Outcome results
None listed