A comparison of non-deceptive placebo treatment and cognitive reappraisal for disgust regulation: an fMRI investigation

A comparison of non-deceptive placebo treatment and cognitive reappraisal for disgust regulation: an fMRI investigation - OLP and disgust regulation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00029250

Enrollment

150

Registered

2022-06-08

Start date

2022-06-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

healthy subjects

Interventions

Group 1: Passive viewing of disgustring and neutral images Group 2: Viewing of disgusting and neutral images after placebo intake Group 3: Viewing of disgusting and neutral images with cognitive reap

Eligibility

Sex/Gender

Female

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: age between 18 and 60 years; female

Exclusion criteria

Exclusion criteria: diagnoses of mental/ neurological disorders, psychotropic medication; contraindication MRI

Design outcomes

Primary

Measure	Time frame
Comparison of brain activity while viewing disgusting/ neutral pictures between the three groups (passive viewring, reappraisal, placebo) via fMRI	—

Secondary

Measure	Time frame
Comparison of affective ratings (intensity of experienced disgust while viewing disgust images) between the three groups via a Likert scale	—

Countries

Austria

Contacts

Public ContactAnne Schienle

Universität Graz

anne.schienle@uni-graz.at+43 316 380-5086

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026