healthy volunteers
Conditions
Interventions
Group 1: Investigation of radical production without cigarette smoke exposure.
Group 2: Investigation of radical production with cigarette smoke.
Group 3: Investigation of radical production without c
Sponsors
Charité-Universitätsmedizin Berlin, Dermatologie
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: The studies will be performed on study participants who are - are > 18 years old and have no skin diseases - have given written informed consent - have a skin type of I-III (Fitzpatrick) - Informed about the aims of the study and the nature of the examinations
Exclusion criteria
Exclusion criteria: Exclusion Criteria: - Minors - Persons wearing metallic implants in the area of the forearm (screws, pins, etc. ) - Persons wearing tattoos in the area of the inner forearm - nursing mothers and women with known pregnancy - known skin diseases - skin type >III (Fitzpatrick) - intensive sun exposure on the skin areas to be irradiated on the inner forearm within the last 14 days before the irradiation date - test persons who are shorter than 1,60m - Subjects who are not able to make decisions on their own responsibility
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Detection of radicals after exposure to cigarette smoke using confocal Raman microscopy (CRM) . | — |
Secondary
| Measure | Time frame |
|---|---|
| Demonstration of the protective effect against cigarette smoke-induced radical formation by a cream formulation. | — |
Countries
Germany
Contacts
Public ContactMartina Meinke
Charité-Universitätsmedizin Berlin, Dermatologie
Outcome results
None listed