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Guillain-Barré syndrome: patient characteristics and early symptoms as potential predictors of later outcome and degree of independence - a retrospective analysis

Guillain-Barré syndrome: patient characteristics and early symptoms as potential predictors of later outcome and degree of independence - a retrospective analysis

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00029223
Enrollment
130
Registered
2022-06-13
Start date
2022-06-16
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

G61.0

Interventions

Group 1: Within the framework of a monocentric observational study, the data of all GBS cases who were admitted to a German early rehabilitation clinic as inpatients between 1999 and 2021 and who meet

Sponsors

Lehrstuhl für Neurologie an der Universität Witten/Herdecke
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: - Diagnosis of Guillain-Barré syndrome confirmed according to the diagnostic guidelines of the German Society of Neurology and GBS is the main diagnosis for the rehabilitation measure. - acute GBS with the ICD-10 code G61.0 of the variants Acute Inflammatory Demyelising Polyneuropathy, Acute Motor Axonal Polyneuropathy, Acute Motor Sensory Axonal Polyneuropathy or the Miller-Fisher Syndrome - Patient must be at least 18 years old - Inpatient stay at Rehanova, which ended by 30.06.2021 and lasted at least 14 days - referral was made by the hospital where the diagnosis of GBS was made and the rehabilitation immediately followed the hospital stay - in the case of interruption and later resumption of the rehabilitative measure (e.g. due to necessary transfer to a hospital), the period of interruption was shorter than three months Translated with www.DeepL.com/Translator (free version)

Exclusion criteria

Exclusion criteria: - Diagnosis of GBS is listed as an unconfirmed suspected diagnosis. - Presence of chronic GBS or an acute variant other than those mentioned above (e.g. Elsberg syndrome). - the patient was transferred to Rehanova from another rehabilitation facility - it is not the first rehabilitation for the disease, but a renewed measure due to residual symptoms

Design outcomes

Primary

MeasureTime frame
In order to depict the degree of independence, the changes in the assessment values of the Early Rehabilitation Bartel Index (FRB), the Bartel Index (BI) and the Early Rehabilitation Index (FRI) from the beginning to the end of rehabilitation are determined as primary outcomes. The change in walking ability and the change in the assessment values of the individual items of the FRB during the course of the stay are used as the primary endpoint for the representation of the functional outcome.

Secondary

MeasureTime frame
The change in the rehabilitation phase during the rehabilitation period is defined as a secondary target value. This classification into the phases B-D of the BAR allows conclusions to be drawn about the patient's need for help, the responsible payer of the rehabilitation measure and the amount of costs assumed by the payer.

Countries

Germany

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026