A41.9 K59.9
Conditions
Interventions
Group 1: A longitudinal examination of the gut, tracheal, and pharyngeal microbiome in cardiac surgery patients who do not demonstrate septic complications perioperatively.
Group 2: A longitudinal exa
Sponsors
Klinik für Anästhesiologie, Intensiv-, Notfall- und SchmerzmedizinUniversitätsklinikum Heidelberg
Eligibility
Sex/Gender
All
Age
0 Years to 12 Years
Inclusion criteria
Inclusion criteria: - Written informed consent by the legal guardians of the study participant - Newborn age up to and including 12 years
Exclusion criteria
Exclusion criteria: - Refusal of participation in the study by legal representatives - Age >12 years - Pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Does the enteric microbiome return to baseline (residence) after 12 months at the latest and thus recover from initial antibiotic therapy? | — |
Secondary
| Measure | Time frame |
|---|---|
| Is there a change in the enteric microbiome due to the administration of antibiotics in children and youths who had not previously received antibiotic therapy? Can the microbiome analysis also provide a prognostic statement about the outcome of the patients? Can a correlation be shown between the results from the oral swabs, tracheal secretions, and stool samples? | — |
Countries
Germany
Contacts
Public ContactKevin Tourelle
Klinik für Anästhesiologie, Intensiv-, Notfall- und SchmerzmedizinUniversitätsklinikum Heidelberg
Outcome results
None listed