Anti-HDV and HDV-RNA prevalence in HBsAg positive blood samples prospectively collected in the hepatitis B screening within the “Check-Up35+” in the German primary care setting after implementation by the Federal Joint Committee (G-BA)

Anti-HDV and HDV-RNA prevalence in HBsAg positive blood samples prospectively collected in the hepatitis B screening within the “Check-Up35+” in the German primary care setting after implementation by the Federal Joint Committee (G-BA) - Delta-Screening within the "Check-Up 35+"

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00029180

Enrollment

150000

Registered

2022-06-02

Start date

2022-01-01

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

B17.0

Interventions

Group 1: A retrospective and prospective analysis of the laboratory database of the LADR laboratory network (11 locations) is carried out. The primary aim of the study is to prospectively determine t

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: for the prospective part of the study: - Age 18-99 years - HBsAg positive result within the Check-Up35+ - written informed consent for the analysis of HDV-RNA and documentation of clinical parameters for the retrospective part of the study: - Age 18-99 years - HBsAg positive result within the routine diagnostic evaluation of primary care physicians

Exclusion criteria

Exclusion criteria: no specific exclusion criteria

Design outcomes

Primary

Measure	Time frame
prevalence of anti-HDV in HBsAg positive individuals in the prospectively analysed blood samples of the “Check-Up 35+”	—

Secondary

Measure	Time frame
- prevalence of HDV-RNA in HBsAg and anti-HDV positive individuals in the prospectively analysed blood samples of the “Check-Up 35+” - prevalence of anti-HDV in HBsAg positive individuals in the retrospective LADR database analysis - prevalence of HDV-RNA in HBsAg and anti-HDV positive individuals in the retrospective LADR database analysis - anti-HDV screening rate in HBsAg positive patients by primary care physicians in Germany	—

Measure

Time frame

- prevalence of HDV-RNA in HBsAg and anti-HDV positive individuals in the prospectively analysed blood samples of the “Check-Up 35+” - prevalence of anti-HDV in HBsAg positive individuals in the retrospective LADR database analysis - prevalence of HDV-RNA in HBsAg and anti-HDV positive individuals in the retrospective LADR database analysis - anti-HDV screening rate in HBsAg positive patients by primary care physicians in Germany

—

Countries

Germany

Contacts

Public ContactJohannes Wiegand

Universitätsklinikum LeipzigKlinik für Gastroenterologie

johannes.wiegand@medizin.uni-leipzig.de+493419712330

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 5, 2026