F53.0 F53.1
Conditions
Interventions
Group 1: Primiparous pregnant or postpartum women
Examination time points: optionally in the 2nd/3rd trimester of pregnancy, within 1-6 days after delivery, 3 weeks, 6 weeks, 9 weeks, 12 weeks and 24
Sponsors
Uniklinik RWTH AachenKlinik für Psychiatrie, Psychotherapie und Psychosomatik
Eligibility
Sex/Gender
Female
Age
18 Years to 45 Years
Inclusion criteria
Inclusion criteria: Pregnant or postpartum women: healthy, full-term primiparous pregnancy (> 37 weeks gestation). Nulliparous women: age-matched with postpartum women, never been pregnant regardless of pregnancy outcome (e.g., extrauterine pregnancy or spontaneous abortion)
Exclusion criteria
Exclusion criteria: All participants: no alcohol or psychotropic substance dependence or use (during pregnancy), no acute depression or depression (during pregnancy), no acute or previous psychosis or manic episodes. Postpartum women: Mothers of infants who are in the intensive care unit after delivery. MRI: pacemaker or implantable defibrillator; plates, pins, screws, or metal mesh used to repair bones or joints; metal implants; metal jewelry, including an implanted or external drug pump; epilepsy; or claustrophobia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Model of the peri- and postpartum brain starting at time from childbirth: structural and functional plasticity in the postpartum period and investigating if and when the maternal brain returns to its pre-pregnancy state (comparison with nulliparous women). | — |
Secondary
| Measure | Time frame |
|---|---|
| Model of postpartum neuroplasticity and associated risk and modulating factors (physical health, hormones) and their impact on infant attachment and cognitive performance. | — |
Countries
Germany
Contacts
Public ContactNegin Daneshnia
Uniklinik RWTH AachenKlinik für Psychiatrie, Psychotherapie und Psychosomatik
Outcome results
None listed