Neuropsychological Assessment of Cognitive Impairment in Kidney Transplantation (NAsKiT) and its Related Risk Factors

Neuropsychological Assessment of Cognitive Impairment in Kidney Transplantation (NAsKiT) and its Related Risk Factors - NAsKiT

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00029164

Enrollment

100

Registered

2022-05-27

Start date

2021-02-01

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

N18.5

Interventions

Group 1: Observational study 1st group: patients who are not yet transplanted. Testing is performed here before transplantation and then 3 months and 12 months after transplantation. 2nd group: pati

Eligibility

Sex/Gender

All

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Individuals who are going to receive a kidney transplantation (immediate – deceased kidney donor, or within the next two weeks – living kidney donors) or have already received a kidney transplantation in the past will be included in this study. Due to the use of a standardized psychological assessment, individuals have to be native German speakers and at least 18 years of age.

Exclusion criteria

Exclusion criteria: Individuals under the legal supervision of a caretaker and with preexisting psychiatric disorder have to be excluded from the study.

Design outcomes

Primary

Measure	Time frame
The primary outcome measure will be a) the effect of kidney transplantation of the cognitive performance up to 12 months after transplantation (part A) and b) the development of cognitive performance following kidney transplantation over time (part B).	—

Secondary

Measure	Time frame
As a secondary outcome, we will assess a distinct profile of cognitive function using standard neurocognitive tests. Furthermore, we explore the impact and temporal development of a set of risk factors for deficits in cognitive performance. Second, we want to examine the extent to which cognitive impairment affects depression at all follow-up time points. Third, we want to assess how stressors negatively or positively affect cognitive performance. Fourth, we want to investigate to what degree cognitive performance affects the formation and development of donor-specific antibodies.	—

Measure

Time frame

As a secondary outcome, we will assess a distinct profile of cognitive function using standard neurocognitive tests. Furthermore, we explore the impact and temporal development of a set of risk factors for deficits in cognitive performance. Second, we want to examine the extent to which cognitive impairment affects depression at all follow-up time points. Third, we want to assess how stressors negatively or positively affect cognitive performance. Fourth, we want to investigate to what degree cognitive performance affects the formation and development of donor-specific antibodies.

—

Countries

Germany

Contacts

Public ContactHristos Karakizlis

Universitätsklinikum Giessen und Marburg, Standort Giessen

hristos.karakizlis@innere.med.uni-giessen.de064198557944

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Mar 14, 2026