Evaluating the systemic level of inflammation in Relation to the perioperativ Outcome of Patients with pre-existing cardiovascular diseases in non-cardiac surgery

Evaluating the systemic level of inflammation in Relation to the perioperativ Outcome of Patients with pre-existing cardiovascular diseases in non-cardiac surgery - InflammHeart

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00029162

Enrollment

Registered

2022-05-31

Start date

2022-07-15

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aneurysms of the descending thoracic aorta and/or abdominal aorta

Interventions

Group 1: 20 Patients with cardiovascular pre-existing diseases in non-cardiac surgery

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: planned, open vascular surgery of the aorta Revised Cardiac Index >=2

Exclusion criteria

Exclusion criteria: Pregnancy, lactation, participation in any other prospective interventional study during participation in this study. Patients who are incapable of giving consent. Patients who are in hospital because of an administrative order.

Design outcomes

Primary

Measure	Time frame
This pilot study - in the context of clinical routine - is intended to estimate the effect and the case number planning for subsequent studies. The following endpoints will be registered: Vital signs and their indices (oxygen saturation, blood pressure, heart rate, heart rhythm, cardiac index, stroke volume, stroke volume variation, stroke volume index, pulse pressure variation, central venous pressure, lactate, base excess, haemoglobin content, creatinine concentration, central venous saturation, diuresis), duration of surgery, anaesthesia duration, ventilation duration, ventilation parameters, intraoperative blood loss, need for blood products, catecholamine doses, incidence of organ complications, duration of dialysis, echocardiography parameters (presence of pericardial effusion, size of atria and ventricles, presence of vitia, ejection fraction, assessment of heart valves), cytokine levels, length of stay (ICU, hospital).	—

Measure

Time frame

This pilot study - in the context of clinical routine - is intended to estimate the effect and the case number planning for subsequent studies. The following endpoints will be registered: Vital signs and their indices (oxygen saturation, blood pressure, heart rate, heart rhythm, cardiac index, stroke volume, stroke volume variation, stroke volume index, pulse pressure variation, central venous pressure, lactate, base excess, haemoglobin content, creatinine concentration, central venous saturation, diuresis), duration of surgery, anaesthesia duration, ventilation duration, ventilation parameters, intraoperative blood loss, need for blood products, catecholamine doses, incidence of organ complications, duration of dialysis, echocardiography parameters (presence of pericardial effusion, size of atria and ventricles, presence of vitia, ejection fraction, assessment of heart valves), cytokine levels, length of stay (ICU, hospital).

—

Countries

Germany

Contacts

Public ContactSascha Treskatsch

Charité Campus Benjamin FranklinKlinik f. Anästhesiologie m. S. operative Intensivmedizin

Anästhesiologie-cbf@charite.de+4930450551522

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026