Graft complications and survival rates in patients with oral squamous cell carcinoma - a retrospective evaluation investigating the impact of CAD/CAM.

Graft complications and survival rates in patients with oral squamous cell carcinoma - a retrospective evaluation investigating the impact of CAD/CAM. - /

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

DRKS

Registry ID

DRKS00029159

Enrollment

348

Registered

2022-06-20

Start date

2020-01-30

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

C04.8

Interventions

Group 1: Patients with conventional surgery method Group 2: Patients with CAD/CAM method

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients who underwent primary microsurgical reconstruction of the oral cavity due to OSCC in the Clinic of Oral and Maxillofacial Surgery, Medical Center — University of Freiburg, Germany between 2000 and 2019 and patients with osteoradionecrosis following OSCC.

Exclusion criteria

Exclusion criteria: Patients with other tumors than OSCC, patients with neoadjuvant therapy due to other treatments before surgery and patients who haven’t had microsurgical reconstruction.

Design outcomes

Primary

Measure	Time frame
Occurence of transplant complications and survival rates in patients after microsurgical surgery.	—

Secondary

Measure	Time frame
Impact on patient specific risk factors regarding transplant complications and survival rates of the patients.	—

Countries

Germany

Contacts

Public ContactLeonard Simon Brandenburg

Universitätsklinikum Freiburg, Department für Mund-, Kiefer- und Gesichtschirurgie

leonard.brandenburg@uniklinik-freiburg.de076127048710

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 7, 2026