“Comparative evaluation of Cissus quadrangularis gel and Platelet rich fibrin in Treatment of Intrabony Defects in Chronic Periodontitis Patients - A clinical study”

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

DRKS

Registry ID

DRKS00029128

Enrollment

Registered

2022-05-30

Start date

2020-12-20

Completion date

Unknown

Last updated

2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K05.6 K05.6

Interventions

Group 1: Open flap debridement Group 2: Open flap debridement with placement of Cissus quadrangularis gel Group 3: Open flap debridement with placement of Platelet rich fibrin

Eligibility

Sex/Gender

All

Age

30 Years to 55 Years

Inclusion criteria

Inclusion criteria: Patients diagnosed with generalized periodontitis as per World Workshop Classification criteria - 2017 with age group of 30-55 years, who had not received periodontal therapy, within preceding six months with periodontal pocket depth of = 5mm after phase I periodontal therapy and presence of 2-or 3-walled intra-bony defects (IBDs) with radiographic depth =3mm and platelet count more than 2,00,000/mm3.

Exclusion criteria

Exclusion criteria: Smokers, alcoholics, pregnant, lactating females, post-menopausal women, patients with vitamin D deficiency, systemically compromised patients and those on medications (corticosteroids/ bisphosphonate, statin therapy, blood thinners) that may interfere with wound healing, patients with grade II and grade III tooth mobility.

Design outcomes

Primary

Measure	Time frame
Bone fill percentage over 3, 6, 9 months	—

Secondary

Measure	Time frame
Periodontal regeneration	—

Countries

India

Contacts

Public ContactSandhya Sri S

The Oxford Dental College

mailsandhya29@gmail.com7406442114

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026