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Sex steroid hormones influence new bone formation rate after iliac onlay grafting: A prospective clinical pilot study

Sex steroid hormones influence new bone formation rate after iliac onlay grafting: A prospective clinical pilot study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
DRKS
Registry ID
DRKS00029123
Enrollment
24
Registered
2022-06-24
Start date
2008-09-03
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

K08.2

Interventions

Group 1: Postmenopausal women with severe alveolar bone atrophy and less than 5 mm residual alveolar bone height. Group 2: Men with severe alveolar bone atrophy and less than 5 mm residual alveolar bo

Sponsors

Klinik für Mund-, Kiefer-, Gesichtschirurgie Charité Berlin
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: severe resorption of the jaw with a remaining bone volume of less than 5 mm in height, partially/completly endentolous upper/lower jaw

Exclusion criteria

Exclusion criteria: Hormone supplementation, periodontitis, diabetes, history of ovariectomy, immunosuppression, cardio-vascular diseases, irradiation and chemotherapy were exclusion criteria. Nicotine users and patients aged <18 years or participating in other studies were excluded in the present study.

Design outcomes

Primary

MeasureTime frame
New bone formation rate based on histomorphometric measure (Masson-Trichrome-Goldner staining) of bone sample gained at the time of implant insertion, 3 months after bone grafting.

Secondary

MeasureTime frame
implant survival rate

Countries

Germany

Contacts

Public ContactVictoria Landwehr

Klinik- fur Mund-, Kiefer- und Gesichtschirurgie

victoria.landwehr@uniklinik-freiburg.de0761/270-49820

Outcome results

None listed

Source: DRKS (via WHO ICTRP) · Data processed: Feb 4, 2026