Physiological study in healthy participants. No health problem will be investigated
Conditions
Interventions
Group 1: Single-arm interventional trial:
The intervention consists of an acute aerobic exercise bout over 45 minutes at a moderate intensity (60% maximal performance capacity).
Sponsors
TU Dortmund, Institut für Sport und Sportwissenschaft, Arbeitsbereich für Leistung und Gesundheit (Sportmedizin)
Eligibility
Sex/Gender
All
Age
20 Years to 35 Years
Inclusion criteria
Inclusion criteria: Age: 20-35 years German speaking (fluent) BMI < 30
Exclusion criteria
Exclusion criteria: Chronic previous disease - Regular medication use at the time of study participation or in the preceding 6 months - Pregnancy or breastfeeding - Use of oral contraception - Drug use in the past 6 months - Acute infection or orthopedic injury - Intake of nutritional supplements - Smoking:in - > 300 minutes of endurance training per week (within the last 6 months) - > 3 strength training sessions per week (within the past 6 months)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary endpoint is the serum concentration of kynurenic acid | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary endpoints include serum concentrations of all other tryptophan metabolites, humoral and cellular markers of inflammation, expression of enzymes along the KP in circulating immune cells, and subjective well-being | — |
Countries
Germany
Contacts
Public ContactPhilipp Zimmer
TU Dortmund, Institut für Sport und Sportwissenschaft, Arbeitsbereich für Leistung und Gesundheit (Sportmedizin)
Outcome results
None listed